What Happens When You Vape? E Cigarettes May Cause COPD. Here's Why Prince Court Medical Centre A new study published in Nicotine & Tobacco Research found that those using e cigarettes alone were more than twice as likely to develop COPD than people who didn't use any tobacco products, Vaping May Seem Safer Than Cigarette Smoking, but It Still Raises Lung Disease Risk The Impact of E Cigarettes and Asthma: What You Need to Know