Smoking (or vaping) doesn't affect your ability to donate blood. Help us bust this myth by sharing our post. Can Vaping Cause Lung Cancer? Here's What We Know. Can You Donate Blood If You Smoke? Cannabis, Nicotine, and More We all know smoking and vaping isn't great for your health. But it doesn't stop you from being a blood or plasma donor. Just make sure to wait one hour after donating Can Smokers Donate Blood in India & its Side Effects?