A new class of drugs called senolytics works by hunting down and destroying senescent "zombie cells" that accumulate with age and drive wrinkles, weak bones, and organ decline. In an early human Targeting Senescence: A Review of Senolytics and Senomorphics in Anti Aging Interventions Development of a novel senolytic by precise disruption of FOXO4 p53 complex eBioMedicine Peptide inhibitors targeting FOXO4 p53 interactions and inducing senescent cancer cell specific apoptosis bioRxiv Senotherapy for chronic lung disease Pharmacological Reviews
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foxo4-dri senolytic human trial Development of a novel senolytic by precise disruption of FOXO4-p53 complex