Dihexa (also known as PNB 0408) is an experimental small molecule derived from angiotensin IV. It was engineered to cross the bloodbrain barrier and has shown synaptogenic effects in preclinical models. The often quoted Targeting redox altered plasticity to reactivate synaptic function: A novel therapeutic strategy for cognitive disorder ScienceDirect Synaptic Plasticity Synapses Neurology TeachMePhysiolgy Dihexa Research Grade Neurotrophic Molecule 20 mg PRG Abnormal synaptic plasticity and impaired cognition in schizophrenia