PeerJ Nrf2 pathway activation promotes the expression of genes related to glutathione metabolism in alcohol exposed astrocytes Alcohol and paracetamol are both processed through the liver. Paracetamol can form a toxic metabolite called NAPQI, which the body usually neutralises safely. But factors like heavy alcohol use, repeated dosing, fasting, Alcohol Induced Oxidative Stress and the Role of Antioxidants in Alcohol Use Disorder: A Systematic Review Adaptations in glutathione based redox protein signaling pathways and alcohol drinking across species ScienceDirect Glutathione (GSH) Intracellular Antioxidant, Liver Support