Autism & Undermethylation; Mitochondria, Oxidative Stress, Folate The Role of Glutathione Metabolism in Chronic Illness Development and Its Potential Use as a Novel Therapeutic Target Cureus I've spent 16 years as an RECE working alongside children and the families who are doing everything they can for them. So when I found research connecting glutathione depletion to autism it Studies show children with autism have significantly lower levels of glutathione, the body's master antioxidant. Without enough glutathione, the body struggles to eliminate toxins, making it harder to cope with everyday Oxidative Stress in Autism Spectrum Disorder Molecular Neurobiology Springer Nature Link