Pigmented Oral Lesions: Clues to Identifying the Potentially Malignant Consultant360 Brown spots, especially on the lips, can be alarming to some. In some instances it can indicate rare oral mucosal melanoma, however in this case it was a non cancerous labial melanotic macule. Pigmented Lesions of the Oral Mucosa Pocket Dentistry A Case Report of Oral Malignant Melanoma: A Silent Killer Cureus Melanotic Macules, Naevi, and Melanoma Springer Nature Link