Hemolytic Anemias Part 4: G6PD Deficiency; Pathophysiology,Morphology, clinical features The Biological Functions of Glutathione Encyclopedia MDPI Although G6PD deficiency, which can cause problems in red blood cells upon certain triggers, is the most common human enzyme defect, affecting over 400 million people, including over 1 in 10 Black Glutathione, H2O2, & Red Blood Cells @ Metabolism Made Easy Oxidative Stress in Healthy and Pathological Red Blood Cells