Multiscale modelling approach combining a kinetic model of glutathione metabolism with PBPK models of paracetamol and the potential glutathione deplet Integrative Biology (RSC Publishing) DOI:10.1039 C3IB20245C Mini Review Acetaminophen Toxicity and 5 Oxoproline (Pyroglutamic Acid): A Tale of Two Cycles, One an ATP Depleting Futile Cycle SAT 071 Acquired 5 oxoproline acidosis: A rising concern Kidney International Reports Pro GA Cell permeable GGCT inhibitor,FDV 0019 5 Oxoprolinuria What is it: Aka pyroglutamic acidosis, GrepMed
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5-oxoproline glutathione Full article: What is the clinical significance of 5-oxoproline (pyroglutamic acid) in high anion gap metabolic acidosis following paracetamol (acetaminophen) exposure?