OTC, NOT RISK FREE: We're getting more calls than usual about acetaminophen, the active ingredient in Tylenol. Many over the counter (OTC) products contain a mix of pain and fever reducers, cough suppressants, and other Old and New Analgesic Acetaminophen: Pharmacological Mechanisms Compared with Non Steroidal Anti Inflammatory Drugs Sex differences in glutathione metabolism and acetaminophen toxicity Acetaminophen (brand name Tylenol) is found in hundreds of prescription and over the counter medicines. Taking more than directed can cause serious health problems. Always read medicine labels and follow the instructions carefully. If Acetaminophen causes neurodevelopmental injury in susceptible babies and children: no valid rationale for controversy