The Metabolism of Acetaminophen and the Synthesis of Glutathione Download Scientific Diagram Myth busting, Acetaminophen version. "Avoid Acetaminophen (Tylenol) because it causes glutathione depletion". Truth?? As a pediatrician and ER doctor and as moms we're often asked about this. And we understand why: Acetaminophen & the kidney Renal Fellow Network What Is Acetaminophen? Definition, Uses, Side Effects, and Risks Olympic Behavioral Health Metabolism of acetaminophen (paracetamol) in plantstwo independent pathways result in the formation of a glutathione and a glucose conjugate Environmental Science and Pollution Research Springer Nature Link