Dihexa (also known as PNB 0408) is an experimental small molecule derived from angiotensin IV. It was engineered to cross the bloodbrain barrier and has shown synaptogenic effects in preclinical models. The often quoted Small molecule activation of the neurotrophin hepatocyte growth factor to treat Alzheimer disease Dihexa Research Peptide Protocols: Reconstitution & Storage HGF c MET pathway in cancer: from molecular characterization to clinical evidence Oncogene Hepatocyte Growth Factor MET Activator Rescues Working Memory Deficits after Repeated Mild Traumatic Brain Injury Katelyn A. Martino, Arush Nakhre, Renee M. Demarest, David M. Devilbiss, 2025
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dihexa hgf/c-met agonist Structural basis of the activation of c-MET receptor