Toxins and Methylation Glutathione & Copper Overload Pathways Estrogen Metabolism, Detoxification, and Methylation Dr. Daniel Metzger, DACM, L.Ac. Alterations in Histone H4 Lysine 20 Methylation: Implications for Cancer Detection and Prevention Semantic Scholar Your blood tests are normal. Your sleep is adequate. You're still exhausted. This is the most common presentation I see in clinic and the answer is almost never found on a Under high oxidative stress, the body prioritizes glutathione production over methylation. Protect cells, DNA, and lipids first before building and detoxifying. #KalishInstitute #FunctionalMedicine