Pigmented Oral Lesions: Clues to Identifying the Potentially Malignant Consultant360 Pigmented (Purple or Brown) Lesions in the Mouth Pigmented (Purple or Brown) Lesions in the Mouth Kazemi Oral Surgery Facialart.com Taint melanotic of the lip vaporization laser UNILASER MDICA What Caused These Multiple Hyperpigmented Macules of the Mouth? Brown spots, especially on the lips, can be alarming to some. In some instances it can indicate rare oral mucosal melanoma, however in this case it was a non cancerous labial melanotic macule.