Peptide Therapy in Atlanta Xperience Health Leopard skin appearance on colonoscopy. Melanosis coli is a condition characterized by dark brown or black pigmentation of the colon lining, often resulting from the prolonged use of anthraquinone laxatives like senna This is a very rare case of metastatic oral mucosal melanoma to the colon with an unusual presentation mimicking melanosis coli. The colonoscopy findings show no mass effect but multiple hyperpigmented lesions Women's Health Supplements Town & Country Compounding Endoscopic findings of different grades and severities of melanosis Download Scientific Diagram