MTHFR Gene Mutations Explained: Symptoms, Risks & Testing Guide The detox gene (MTHFR) is rendered inactive when your diet is high in meat. Our diet should be 80% plant based or higher. Replying to @brandielorenmakie the MTHFR gene actually has NOTHING to do WITH detoxing, glutathione or vaccines. Also has nothing to do with sugar bugs, sacral dimples, tongue ties and has no Methylation: Impact of Toxins and Heavy Metals on Methylation Methylenetetrahydrofolate reductase (MTHFR) 677C>T rs1801133 genetic variant, homocysteine, folate, and vitamin B12 levels in patients with multiple sclerosis: a scoping review Multiple Sclerosis and Related Disorders