FOXO4 DRI: The Senolytic Peptide That Targets Zombie Cells and Aging Revolution Health & Wellness FOXO4 DRI induces keloid senescent fibroblast apoptosis by promoting nuclear exclusion of upregulated p53 serine 15 phosphorylation Communications Biology Peptide inhibitors targeting FOXO4 p53 interactions and inducing senescent cancer cell specific apoptosis bioRxiv Development of a novel senolytic by precise disruption of FOXO4 p53 complex eBioMedicine Senolytics: from pharmacological inhibitors to immunotherapies, a promising future for patients' treatment npj Aging
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foxo4-dri senolytic human trial Peptide inhibitors targeting FOXO4-p53 interactions and inducing senescent cancer cell-specific apoptosis