Hepatic Glutathione Synthesis: The Liver's Antioxidant Powerhouse Glutathione (GSH) is the most abundant intracellular antioxidantand the liver is its primary production site. Through a tightly regulated, ATP dependent pathway, hepatocytes Glutathione equilibrium (GSH GSSG) following Gln Glu homeostasis. Download Scientific Diagram Molecular Vision: De Donatis, Mol Vis 2010; 16:1025 1033. Figure 1 Glutathione system enhancement for cardiac protection: pharmacological options against oxidative stress and ferroptosis Cell Death & Disease Figure 1 from Dossier : Oxidative stress pathologies and antioxidants The importance of glutathione in human disease Semantic Scholar