Acetaminophen (Paracetamol) Springer Nature Link Acetaminophen Toxicity: How Genetic Susceptibility Combines with Environmental Factors Your livers unsung hero: Glutathione , Lets talk about what really happens when you take Tylenol (acetaminophen)., Your liver breaks down acetaminophen through several pathways. One pathway creates Researchers are studying a possible link between acetaminophen (Tylenol) use during pregnancy and higher autism or ADHD risk. It may lower glutathione, an important antioxidant for brain development. Illustration of the effects of acetaminophen on glutathione, Download Scientific Diagram