Can Sulforaphane Treatment Of Autism Make A Difference? I predict sulforaphane will surpass creatine in the next five years. Sulforaphane activates the NRF2 pathway, which drives glutathione and the bodys core detox systems, helping to reduce Sulforaphane for Liver Health Sulforaphane is a food derived compound with a few core mechanisms. Nrf2 Activation for Phase II support being the primary mechanism. Increased glutathione production Increased phase II enzymes (GST, Metabolism of 4 methylsulphinylbutyl glucosinolate and Download Scientific Diagram Frontiers Glutathione: A Samsonian life sustaining small molecule that protects against oxidative stress, ageing and damaging inflammation