Mechanism of acetaminophen induced hepatotoxicity. High dose of Download Scientific Diagram Tylenol and glutathione, actually explainedhere's the bullet points: * Lots of concern raised on social media re: glutathione depletion and acetaminophen use * Glutathione is used in the metabolism of acetaminophen and Acetaminophen metabolism PARACETAMOL DEPLETES GLUTATHIONE Natural Healing Centre Could Tylenol be making your child's health worse? Acetaminophen is widely used for pain and fever relief, but research suggests it depletes glutathione, a powerful antioxidant essential for immune function,