Obesity pharmacotherapy in older adults: a narrative review of evidence International Journal of Obesity Zepbound beats CagriSema in head to head trial : r Zepbound CagriSema vs Tirzepatide: Weight Loss Results in REDEFINE 4 Trial Paramesh Shamanna posted on the topic LinkedIn Coadministered Cagrilintide and Semaglutide in Adults with Overweight or Obesity New England Journal of Medicine In the REDEFINE 2 phase 3a trial involving adults with obesity and diabetes, the use of cagrilintidesemaglutide resulted in a significantly lower body weight than placebo at 68 weeks. Full trial results