Effects and mechanism of L Carnitine on weight loss Critical Role of Mitochondrial Fatty Acid Metabolism in Normal Cell Function and Pathological Conditions Short Note On Carnitine Shuttle: Fatty acids are oxidized in mitochondria, and synthesized in the cytoplasm. Long chain fatty acids must form an active intermediate, fatty acyl CoA, before being oxidized inside mitochondria. Catherine Activation and Transportation of Fatty Acids to the Mitochondria via the Carnitine Shuttle with Animation Animations PharmaXChange.info L carnitine helps transport fatty acids to produce energy