Glutathione is a critical soldier in our line of defense. We even have mechanisms that recycle and reuse it. But what happens when our toxic burden becomes too high? Our genetic detoxification Glutathione Depletion and Stalwart Anticancer Activity of Metallotherapeutics Inducing Programmed Cell Death: Opening a New Window for Cancer Therapy ACS Omega ACTL6A protects gastric cancer cells against ferroptosis through induction of glutathione synthesis Nature Communications Glutathione overproduction mediates lymphoma initiating cells survival and has a sex dependent effect on lymphomagenesis Cell Death & Disease Glutathione mediated nanomedicines for cancer diagnosis and therapy ScienceDirect