What Is A Melanotic Macule? Labial Lentigo (labial melanotic macule) Cancer Therapy Advisor This lovely patient was thrilled with her beautiful result after laser treatment of oral melanotic macules. I share this case to educate: laser treatment requires accurate diagnosis, an understanding of the differential Metastatic oral malignant melanoma transformed from pre existing pigmented lesions in mandibular gingiva: Report of an unusual case ScienceDirect Pigmented (Purple or Brown) Lesions in the Mouth Pigmented (Purple or Brown) Lesions in the Mouth Kazemi Oral Surgery Facialart.com