Tylenol depletes something called glutathione. Glutathione is a master antioxidant and your first line of protection against environmental toxins. It detoxifies and protects your cells. It protects your immune system and The Metabolism of Acetaminophen and the Synthesis of Glutathione Download Scientific Diagram Myth busting, Acetaminophen version. "Avoid Acetaminophen (Tylenol) because it causes glutathione depletion". Truth?? As a pediatrician and ER doctor and as moms we're often asked about this. And we understand why: Glutathione, Tylenol, and Vaccines: What Parents Need to Know Lotus Homeopathy, Inc. Acetaminophen: The Hidden Dangers and the Genetic Connection MaxGen Labs