Smoker's melanosis Wikipedia Brown spots, especially on the lips, can be alarming to some. In some instances it can indicate rare oral mucosal melanoma, however in this case it was a non cancerous labial melanotic macule. Mucosal melanocytic macules Mystery behind labial and oral melanotic macules: Clinical, dermoscopic and pathological aspects of Laugier Hunziker syndrome A collection of resources for RACGP exams Next Gen GP Text Book live webinars AKT and KFP questions