PDF) Implications of Altered Glutathione Metabolism in Aspirin Induced Oxidative Stress and Mitochondrial Dysfunction in HepG2 Cells Acetaminophen and aspirin toxicity are both high yield, but the injury pattern is very different. Acetaminophen overdose overwhelms glutathione, allowing NAPQI to build up and cause hepatic necrosis. The antidote is N acetylcysteine, which S Acetyl Glutathione by Celarity Boost Glutathione Levels Naturally Glutathione S Transferase M1 and P1 Genotype, Passive Smoking, and Peak Expiratory Flow in Asthma The study does not imply that paracetamol causes asthma and some children do need more paracetamol than the rest for the growing respiratory problems