Oral melanoacanthoma and oral melanotic macule: a report of 8 cases, review of the literature, and immunohistochemical analysis Lipo c Bulk Supply buy from factory 99% Purity powder An oral melanotic macule is a harmless dark spot found on the lip, most often the lower lip, or inside the mouth, either on the gums, inside the cheek, or on the roof of the mouth. An oral melanotic Dark spot on lip appeared randomly : r Blackskincare Search Results: Superior lip, Rash or multiple lesions, 50 59 year old Female