What Causes Gout? Let's Break It Down! Gout is a form of arthritis that strikes suddenlycausing intense pain, redness, and swelling, often in the big toe. But what really causes it? Frontiers Serum uric acid and high sensitivity C reactive protein levels among people living with HIV on dolutegravir and ritonavir boosted atazanavir based antiretroviral therapy: a comparative cross sectional study Gout often thought of as a "rich man's disease" due to its association with rich foods occurs when crystals form in the joints or surrounding tissues, causing pain, inflammation and Uric acid effects on glutathione metabolism estimated by induction of glutamate cysteine ligase, glutathione reductase and glutathione synthetase in mouse J744A.1 macrophage cell line Glutathione, Reduced, Free Acid