Can I Mix Niacinamide With Glutathione APLB Glutathione Niacinamide Cleansing Water YesStyle Combining Glutathione and Niacinamide for skin brightening can be extremely beneficial for your skin. Niacinamide helps reduce pigmentation and dark spots, whereas glutathione helps reduce melanin production, thereby lightening the dark spots Can I Mix Niacinamide With Glutathione Combining Glutathione, Niacinamide, and Vitamin E creates a triple threat formula that targets brightening, barrier repair, and deep protection. Here is a breakdown of the specific benefits of this combination for your Ultra