Pigmented Oral Lesions: Clues to Identifying the Potentially Malignant Consultant360 This lovely patient was thrilled with her beautiful result after laser treatment of oral melanotic macules. I share this case to educate: laser treatment requires accurate diagnosis, an understanding of the differential Mucosal melanocytic macules An 84 year old man with a history of metastatic melanoma of the scalp who was undergoing immunotherapy presented with new, multiple blue gray macules on the scalp. Definition of melanocytic macules associated with Peutz Jeghers syndrome NCI Dictionary of Genetics Terms NCI