Does Glutathione Really Work for Skin Whitening? Facts vs. Myths Glutathione and Vitamin C: Right Dosage for Skin Whitening Can you take glutathione without vitamin C? The simple answer: NO! Glutathione will not work without Vitamin C. Glutathione remains in two states, active and inactive. When it's in its active state, Can you take glutathione without vitamin C? The simple answer: NO! Glutathione will not work without Vitamin C. Glutathione remains in two states, active and inactive. When it's in its active state, Amazon.com: Glutathione Supplement 1,000mg Per Serving, 98% Purity Plus Vitamin C 500mg, Active Reduced Form (GSH) Intracellular Antioxidant Supports Detoxification & Immune Health : Health & Household