Vitamin B12 deficiency can cause symptoms like headaches, fatigue, depressive mood, gastrointestinal issues, and more. While vegetarians are at a higher risk of vitamin B12 deficiency, it can affect non vegetarians too. Check As per my latest article, if you use PPIs chronically, and you're experiencing worsening of migraine symptoms, ask your neurologist if you should try supplementing with magnesium and check your B12. : B12 Injections: Who Should Get Them and How Long Do They Last? Vitamin B12 Injections Energy Boost The Center Medical Ear Nose and Throat An ENT's Guide to Understanding Headache Issues After Botox