Molecular and Immunomodulatory Mechanisms of Statins in Inflammation and Cancer Therapeutics with Emphasis on the NF B, NLRP3 Inflammasome, and Cytokine Regulatory Axes Simvastatin ameliorates oxidative stress levels in HepG2 cells and hyperlipidemic rats ScienceDirect Most practitioners prescribe statins to lower cholesterol But few pause to ask why was cholesterol high in the first place? In Functional Medicine, we see statin side effects not as random Personalized statin therapy: Targeting metabolic processes to modulate the therapeutic and adverse effects of statins: Heliyon Glutathione system enhancement for cardiac protection: pharmacological options against oxidative stress and ferroptosis Cell Death & Disease