Oral Melanotic Macule MEDizzy Definition of melanocytic macules associated with Peutz Jeghers syndrome NCI Dictionary of Genetics Terms NCI Dental Update Malignant oral melanoma: how to spot it and how it is managed Dental Update ORAL MELANOTIC MACULE (OMM) (Also called focal melanosis labial melanotic macule) A benign, localized, flat pigmented lesion of the oral mucosa Caused by a focal increase in melanin production Mucosal melanocytic macules