Cagrilintide & Semaglutide in Overweight Diabetics (REDEFINE 2) NEJM Med Journal Club New in the August 14, 2025, issue of NEJM: CagrilintideSemaglutide for Overweight or Obesity (REDEFINE 1 phase 3a trial) Cagrilintide Semaglutide for Overweight and Diabetes (REDEFINE 2 phase 3a trial) Once weekly cagrilintide for weight management in people with overweight and obesity: a multicentre, randomised, double blind, placebo controlled and active controlled, dose finding phase 2 trial The Lancet Efficacy and safety of once weekly semaglutide 24 mg versus placebo in people with obesity and prediabetes (STEP 10): a randomised, double blind, placebo controlled, multicentre phase 3 trial PDF] Once weekly cagrilintide for weight management in people with overweight and obesity: a multicentre, randomised, double blind, placebo controlled and active controlled, dose finding phase 2 trial. Semantic Scholar
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