AngIV Analog Dihexa Rescues Cognitive Impairment and Recovers Memory in the APP PS1 Mouse via the PI3K AKT Signaling Pathway Dihexa DIHEXA is a neurogenic peptide designed to enhance cognitive function by increasing synaptic density in the brain. Unlike stimulants that offer temporary boosts, Dihexa supports long term brain health improving communication between Is Dihexa an approved and safe treatment for cognitive impairment or neurodegenerative diseases such as Alzheimer disease? Top Dihexa is a synthetic peptide known for its potential cognitive benefits by promoting nerve growth factor (NGF) activity, which supports the growth, maintenance, and survival of neurons in the brain.