Simple cryosurgical treatment of the oral melanotic macule Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics Can a black pigmented lesion of the oral cavity : Journal of Family Medicine and Primary Care Unusual Extensive Physiologic Pigmentation of the Tongue: A Case Report Cureus Brown spots, especially on the lips, can be alarming to some. In some instances it can indicate rare oral mucosal melanoma, however in this case it was a non cancerous labial melanotic macule. Pigmented Lesions of the Oral Mucosa: Clinical Presentation, Histology, and Recommendations for Management