5 Antidote: NAC (N acetylcysteine) NAC replenishes glutathione, restoring the ability to detoxify NAPQI. It's lifesaving if given early. Example: Hospitals use NAC as the standard treatment for APAP overdose. Comprehensive metabolome analyses reveal N acetylcysteine responsive accumulation of kynurenine in systemic lupus erythematosus: implications for activation of the mechanistic target of rapamycin Metabolomics Springer Nature Link N Acetylcysteine (NAC) cannot increase cellular Glutathione levels Glutathione Reporter Is N Acetylcysteine (NAC) Effective as Psychiatric and Neurological Treatment? Where Does the Evidence Lie? The Multifaceted Therapeutic Role of N Acetylcysteine (NAC) in Disorders Characterized by Oxidative Stress Bentham Science