Mechanisms of IGF 1 Mediated Regulation of Skeletal Muscle Hypertrophy and Atrophy IGF 1 Therapy Improves Muscle Size and Function in Experimental Peripheral Arterial Disease ScienceDirect Crucial role of androgen receptor in resistance and endurance trainings induced muscle hypertrophy through IGF 1 IGF 1R PI3K Akt mTOR pathway Nutrition & Metabolism Springer Nature Link Switched things up and have been using my IGF 1 LR3 30 mins pre workout and have been noticing longer lasting pumps and more vascularity so far! 2 more weeks until I cycle Frontiers Sheep recombinant IGF 1 promotes organ specific growth in fetal sheep