A 48 hour fast can turn standard Paracetamol into acute liver failure. Fasting depletes Glutathione, leaving the liver defenseless against toxic NAPQI. Review the latest guidelines on BMJ Best Practice: https: bestpractice.bmj.com topics en us 1010 What is the difference between Glutathione and N Acetylcysteine (NAC)? Figure 1: CMAJ Mechanism of paracetamol toxicity NUS Faculty of Science NUS Faculty of Science overdose and grapefruit ward round stuff
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