While vapes are less harmful than cigarettes, they shouldn't be used by those who don't smoke. Vaping and nicotine can have a harmful effect on the body, especially in children Side effects of vaping without nicotine Infographic: E cigarettes & Cardiovascular Disease World Heart Federation Can Vaping Cause a Headache? Causes, Symptoms & Prevention Vaping: What Parents Need to Know Vaping isn't harmless it's a serious concern. Most vape products contain nicotine, a highly addictive substance that can impact developing brains and overall health.