How Many Packs of Cigarettes are in a Vape? E cigarettes: Facts, stats and regulations Vape vs Cigarette Nicotine: How Many 5% Vape Puffs Equal One Cig? Catecholamine levels with use of electronic and combustible cigarettes 1 standard vape pod does not directly equal 20 packs of cigarettes in terms of nicotine content, but it can contain nicotine equivalent to a pack of cigarettes. A JUUL pod, for