Nicotine free e cigarettes can damage blood vessels Penn Today Smoking is one of the leading risk factors for Peripheral Artery Disease (PAD). The chemicals in both traditional and e cigarettes cause inflammation in blood vessel walls, while nicotine constricts Smoking and Your Heart How Smoking Affects the Heart and Blood Vessels NHLBI, NIH E cigarettes and CV risk: Current state of the evidence for cardiologists eos cigarette Aspire,kanger e cigarette sales director at EOScigarette