HGF c Met 1 integrin signalling axis induces tunneling nanotubes in A549 lung adenocarcinoma cells Life Science Alliance Dihexa (also known as PNB 0408) is an experimental small molecule derived from angiotensin IV. It was engineered to cross the bloodbrain barrier and has shown synaptogenic effects in preclinical models. The often quoted HGF c Met pathway facilitates the perineural invasion of pancreatic cancer by activating the mTOR NGF axis Cell Death & Disease HGFMet Pathway in Regeneration and Drug Discovery Correlation between hypoxia and HGF c MET expression in the management of pancreatic cancer ScienceDirect