Dihexa (also known as PNB 0408) is an experimental small molecule derived from angiotensin IV. It was engineered to cross the bloodbrain barrier and has shown synaptogenic effects in preclinical models. The often quoted The mechanism of action of Dihexa_Chemicalbook Targeting redox altered plasticity to reactivate synaptic function: A novel therapeutic strategy for cognitive disorder ScienceDirect Mitochondrial plasticity and synaptic plasticity crosstalk; in health and Alzheimer's disease Sayehmiri 2024 CNS Neuroscience & Therapeutics Wiley Online Library Drug Evoked Synaptic Plasticity Causing Addictive Behavior Journal of Neuroscience
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dihexa synaptic plasticity Full article: Altered Synaptic Plasticity: Plausible Mechanisms Associated With Viral Infections