Glutathione is a critical soldier in our line of defense. We even have mechanisms that recycle and reuse it. But what happens when our toxic burden becomes too high? Our genetic detoxification Cystathionine Lyase Protects Against Choline Deficient High Fat Diet Induced Metabolic Dysfunction Associated Steatotic Liver Disease Through the CysteineGlutathione Axis in Mice Min Ji Kim, You Ri Park, Gibong Jang, Yong Kwon Han, Isao Ishii, Glutathione disulfide sensitizes hepatocytes to TNF mediated cytotoxicity via IKK S glutathionylation: a potential mechanism underlying non alcoholic fatty liver disease Experimental & Molecular Medicine Glutathione rich yeast extract improves alcohol associated liver diseases through the improvement of mitochondrial dysfunction and oxidative stress by activating SIRT3 ScienceDirect Serum biomarkers for nonalcoholic fatty liver disease: Are we there yet? Editorial