Unraveling the Truth: Is Nicotine Truly a Depressant? e Cigarettes, Vaping and the Risks of Severe Lung Disease Canyonlands Healthcare Nicotine, e cigarettes, cannabis: All pose different risks and all can be hard to stop UCLA Health E cigarettes are likely to cause cancer, including in the lungs and mouth, according to a sweeping review of scientific evidence that challenges their positioning as a safer alternative to smoking. There is E cigarette vapor linked to cancer in mice National Institutes of Health (NIH)